Authors
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Packapong Thuthaisong
Center of Excellence in Natural Products, Department of Chemistry, Faculty of Science, Chulalongkorn University
Author
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Chanpen Chanchao
Department of Biology, Faculty of Science, Chulalongkorn University
Author
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Phanthiwa Khongharat
Department of Biology, Faculty of Science, Chulalongkorn University
Author
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Prinyasawad Techasombooranakit
Mahidol University International School Demonstration School
Author
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Karantharat Sukata
Kornpitacksuksa School
Author
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Yanisa Kanongsri
Montfort College Secondary School
Author
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Kronghathai Raomanachai
Ratwinit Bangkaeo School
Author
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Vearraya Kamtarad
Debsirinphukhaesaraburi School
Author
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Konchanok Sriyuttakrai
Little Lamb International Christian School
Author
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Yuwajuk Pinnakbud
Saengthong Vitthaya School
Author
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Anyapat Tamarree
Mahidol University International School Demonstration School
Author
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Sarana Vanichchinchai
Harrow International School Bangkok
Author
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Apivich Likitlersuang
King Mongkut’s International Demonstration School
Author
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Preecha Phuwapraisirisan
Center of Excellence in Natural Products, Department of Chemistry, Faculty of Science, Chulalongkorn University
Author
Keywords:
Spent Coffee Grounds, Bioassay Guided Isolation, Antioxidant Potential, Bioactive Compounds, Solvent Extraction
Abstract
Spent coffee grounds (SCGs) are a rich source of several bioactive compounds. In this study, we applied bioassay-guided isolation and successed in identifying the active components. All 7 subfractions isolated from ethyl acetate extract were evaluated for antioxidants against DPPH and ABTS. Subfraction SCG-EA2 potentially inhibited against DPPH and ABTS with IC50 values of 1.76 ± 0.14 and 1.56 ± 0.06 (mg/mL), tentative characterization of subfraction SCG-EA2 by 1H-NMR analysis suggested that terpenoids are the major content in this subfraction.
